Hedgehog pathway inhibitors for locally advanced and metastatic basal cell carcinoma: A real-world single-center retrospective review.

Basal cell carcinoma (BCC) is highly curable by surgical excision or radiation.In rare cases, BCC can be locally destructive or difficult to surgically remove.Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50-60% response rate.Long-term toxicity includes muscle spasms and weight loss leading to dose decreases.This retrospective ch

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Déjà vu experiences in healthy subjects are unrelated to laboratory tests of recollection and familiarity for word stimuli

Recent neuropsychological and neuroscientific research suggests that people who experience peppermint smoothie hibiscus more déjà vu display characteristic patterns in normal recognition memory.We conducted a large individual differences study (n = 206) to test these predictions using recollection and familiarity parameters recovered from

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Literacy in a post-truth world

: This theoretical paper examines whether acquiring better literacy skills may help people to be less vulnerable to various types of information disorders such as keracare twist and define cream fake news or conspiracy theories.We start this venture by looking, first, at the relationships between vulnerability to information disorders and literacy

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